Mouse Model for Sublethal Leptospira interrogans Infection
نویسندگان
چکیده
منابع مشابه
Mouse model for sublethal Leptospira interrogans infection.
Although Leptospira can infect a wide range of mammalian species, most studies have been conducted in golden Syrian hamsters, a species particularly sensitive to acute disease. Chronic disease has been well characterized in the rat, one of the natural reservoir hosts. Studies in another asymptomatic reservoir host, the mouse, have occasionally been done and have limited infection to mice younge...
متن کاملComparison of Leptospira interrogans infection in the goats and sheep
Background: Most leptospiral infections in sheep and goat are asymptomatic but may result in high fever, abortion, stillbirth, agalactiae. There is a different foraging behavior between sheep and goat that may cause the different prevalence of Leptospira interrogans infection in sheep and goats. OBJECTIVES: The purpose of the present study was to compare the prevalence of L. interrogans antibod...
متن کاملCanine Leptospirosis Cases and Molecular Screening for Leptospira interrogans Infection
Received: Revised: Accepted: August 22, 2013 October 09, 2013 October 14, 2013 A molecular survey for pathogenic Leptospira spp. in kennelled dogs in Sicily, Italy, showed up to 16% of positive results. A fatal leptospirosis case was confirmed in a stray dog in the city of Palermo in May 2012. The dog, a mixed breed male, was recovered for therapy but died within an hour. Inflammation was prese...
متن کاملPost-translational Modification of LipL32 during Leptospira interrogans Infection
BACKGROUND Leptospirosis, a re-emerging disease of global importance caused by pathogenic Leptospira spp., is considered the world's most widespread zoonotic disease. Rats serve as asymptomatic carriers of pathogenic Leptospira and are critical for disease spread. In such reservoir hosts, leptospires colonize the kidney, are shed in the urine, persist in fresh water and gain access to a new mam...
متن کاملMultilocus sequence analysis for typing Leptospira interrogans and Leptospira kirschneri.
Fifty-three strains belonging to the pathogenic species Leptospira interrogans and Leptospira kirschneri were analyzed by multilocus sequence analysis. The species formed two distinct branches. In the L. interrogans branch, the phylogenetic tree clustered the strains into three subgroups. Genogroups and serogroups were superimposed but not strictly.
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2015
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.01115-15